Weight Loss Pills That Work

One of the great things about having an internet shop is when people give you positive feedback. Even though I know the stuff we sell works, I'm always pleased when customers have the experience and let me know.

Today I had an email from Tracy Williams in Hampshire (UK) she has been trying the WeightLess weight loss supplement and she told me this:

"I now constantly feel like I have just eaten the largest roast dinner!"

She's only been taking them a few days and is delighted. This really must be one of the best weight loss supplements around.

I also had a very positive comment today about the TENS machine we sell too.

Protest About Broiler Chickens

I don't know if anyone is interested in joining a campaign to help end the suffering of broiler chickens, but River Cottage on channel 4 have started a petition on the following website www.chickenout.tv, to end it, and they need as many supporters as they can find. Hope you can help and give the chickens a brighter new year.

Ginger And Infection

More proof of the efficacy of ginger:

Ginger extract inhibits LPS induced macrophage activation and function
Sudipta Tripathi , David Bruch and Dilip S Kittur
BMC Complementary and Alternative Medicine 2008, 8:1doi:10.1186/1472-6882-8-1
Published:
3 January 2008
Abstract (provisional)

Background
Macrophages play a dual role in host defence. They act as the first line of defence by mounting an inflammatory response to antigen exposure and also act as antigen presenting cells and initiate the adaptive immune response. They are also the primary infiltrating cells at the site of inflammation. Inhibition of macrophage activation is one of the possible approaches towards modulating inflammation. Both conventional and alternative approaches are being studied in this regard. Ginger, an herbal product with broad anti inflammatory actions, is used as an alternative medicine in a number of inflammatory conditions like rheumatic disorders. In the present study we examined the effect of ginger extract on macrophage activation in the presence of LPS stimulation.

Methods
Murine peritoneal macrophages were stimulated by LPS in presence or absence of ginger extract and production of proinflammatory cytokines and chemokines were observed. We also studied the effect of ginger extract on the LPS induced expression of MHC II, B7.1, B7.2 and CD40 molecules. We also studied the antigen presenting function of ginger extract treated macrophages by primary mixed lymphocyte reaction.

Results
We observed that ginger extract inhibited IL-12, TNF-alpha, IL-1 (pro inflammatory cytokines) and RANTES, MCP-1 (pro inflammatory chemokines) production in LPS stimulated macrophages. Ginger extract also down regulated the expression of B7.1, B7.2 and MHC class II molecules. In addition ginger extract negatively affected the antigen presenting function of macrophages and we observed a significant reduction in T cell proliferation in response to allostimulation, when ginger extract treated macrophages were used as APCs. A significant decrease in IFN-gamma and IL-2 production by T cells in response to allostimulation was also observed.

Conclusions
In conclusion ginger extract inhibits macrophage activation and APC function and indirectly inhibits T cell activation.