Wednesday, April 30, 2008
Health Benefits of Chrysanthemum Tea
Chrysanthemum tea is a very popular drink in East Asia and is commonly drank in hot or cold form at places that serve 'yum cha' or in bottled/canned/packed varieties from convenience stores.
Traditionally speaking, chrysanthemum is a highly regarded herb cultivated by ancient Chinese nobility and has been used in Chinese medicine for centuries in the treatment of influenza like symptoms, heatstroke and sore throats. In western herbal medicine, the tea has been used to treat disorders such as varicose veins and atherosclerosis.
The common chrysanthemum tea that you can buy in bottles these days typically contains water, cane sugar and brewed white chrysanthemum and depending on the brand, white tea as well. White tea, which comes from the same tea plant species as Green Tea possesses a similar taste profile and the natural goodness that is found in tea leaves.
Two brands that I've come across which are particular soothing to drink are Pokka (Japanese brand) and Yeo's (Singapore). I like the fact that they're not too sweet with the aroma and taste of chrysanthemum just right.
From: health-fitness
Fitness Quote
Canada's Health System and the Determinants of Health
Canada's Health System and the Determinants of Health
Tuesday, April 29, 2008
Cash Before Chemo
Wall sit
© Healthwise, Incorporated.
This exercise strengthens your back, trunk, and thigh muscles, helping you maintain a healthy lower back.
From MSN Health
Hip flexor stretch
- Kneel on the floor with one knee bent and one leg behind you. Position your forward knee over your foot. Keep your other knee touching the floor.
- Slowly push your hips forward until you feel the stretch in the upper thigh of your rear leg.
- Hold the stretch for 30 seconds. Repeat with the opposite leg.
- Do 3 to 5 times on each side.
Hamstring stretch in doorway
- Lie on your back in a doorway, with one leg through the open door.
- Slide your leg up the wall to straighten your knee. You should feel a gentle stretch down the back of your leg; hold it for 30 to 60 seconds.
- Do not arch your back.
- Do not bend either knee.
- Keep one heel touching the floor and the other heel touching the wall. Do not point your toes.
- Repeat with your other leg.
- Do 3 to 5 times for each leg.
If you do not have a place to do this exercise in a doorway, there is another way to do it:
- Lie on your back and bend the knee of the leg you want to stretch.
- Loop a towel under the ball and toes of that foot, and hold the ends in your hands.
- Straighten your knee and slowly pull back on the towel. You should feel a gentle stretch down the back of your leg; hold it for 30 to 60 seconds.
- Repeat with your other leg.
- Do 3 to 5 times for each leg.
Heel dig bridging
The heel dig bridging exercise works your hamstrings and the muscles around your hip. Do 8 to 12 repetitions. Do not continue with this exercise if it causes pain.
- Lie on your back with both knees bent and your ankles bent so that only your heels are digging into the floor. At this point, your knees should be bent about 90 degrees.
- From here, push your heels into the floor, squeeze your buttocks, and lift your hips off the floor until your shoulders, hips, and knees are all in a straight line.
- Hold briefly, and then slowly lower your hips back down to the floor.
Pelvic tilt exercise
- Lie on your back with your knees bent.
- "Brace" your stomach—tighten your muscles by pulling in and imagining your belly button moving toward your spine. You should feel like your back is pressing to the floor and your hips and pelvis are rocking back.
- Hold for 10 seconds while breathing smoothly.
Prone buttocks squeeze
This exercise strengthens the buttocks muscles, which support the back and help you lift with your legs.
- Lie flat on your stomach with your arms at your sides.
- Slowly tighten your buttocks muscles and hold the position (not your breath) for 5 to 10 seconds. Relax slowly.
- You may need to place a small pillow under your stomach for comfort.
Curl-ups
- Lie on the floor on your back with your knees bent at a 90-degree angle. Your feet should be flat on the floor, about 12 in. (32 cm) from your buttocks.
- Cross your arms over your chest.
- Slowly contract your abdominal muscles and raise your shoulder blades off the floor.
- Keep your head in line with your body; don't press your chin to your chest.
- Hold this position for 1 or 2 seconds, then slowly lower yourself back down to the floor. Repeat 3 to 10 times.
Knee-to-chest exercise
Do not do this exercise if it causes or increases back or leg pain.
- Lie on your back with your knees bent and your feet flat on the floor.
- Bring one knee to your chest, keeping the other foot flat on the floor (or the other leg straight, whichever feels better on your lower back). Keep your lower back pressed to the floor. Hold for 5 to 10 seconds.
- Relax and lower the knee to the starting position. Repeat with the other leg.
- To get more stretch, put your other leg flat on the floor while pulling your knee to your chest.
Alternate arm and leg lifts
Illustration copyright 2005 Nucleus Communications, Inc. All rights reserved. http://www.nucleusinc.com
Lie on your stomach on the floor with your arms straight out ahead of you. Raise your opposite arm and leg (for example, raise your right arm and left leg) a few inches off the floor and hold them there for 5 seconds. Lower them to the floor, and switch to the other arm and leg. Repeat 10 times.
Press-up back extensions
Illustration copyright 2005 Nucleus Communications, Inc. All rights reserved. http://www.nucleusinc.com
Lie on your stomach with your hands under your shoulders. Push with your hands so your shoulders begin to lift off the floor. If it's comfortable, put your elbows on the floor directly under your shoulders so you can rest in this position for several seconds.
Why is it important to do exercises for low back pain?
Exercise and staying active may relieve low back pain and can help speed your recovery.2, 3 Stretching and strengthening your stomach, back, and leg muscles helps make them less susceptible to injury that can cause back pain. Strong stomach, back, and leg muscles also better support your spine, reducing pressure on your spinal discs. This may help prevent disc injury.
Aerobic exercises—such as walking, swimming, or walking in waist-deep water—also help you maintain a healthy back. Aerobic exercise makes your heart and other muscles use oxygen more efficiently. Muscles that frequently receive oxygen-rich blood stay healthier.
Spinal discs
Spinal discs are located between each of the 33 vertebrae, which are the interlocking bones of the spine that are stacked on top of one another. These discs act as shock absorbers for the spine and allow it to flex, bend, and twist.
The outer portion of a spinal disc, called the capsule (annulus fibrosus), is made of tough, elastic cartilage. The capsule surrounds a mass of jelly-like material called the nucleus (nucleus pulposus).
Aging, injury, and illness can cause the spinal discs to crack or rupture. The jelly-like nucleus can leak out, putting pressure on the spinal nerves. Back pain, numbness, and weakness may result, which sometimes requires surgery.
Spinal discs are also called intervertebral discs.
What exercises may reduce low back pain?
Exercises that may help reduce or prevent low back pain include:
- Aerobic exercise, to condition your heart and other muscles, maintain health, and speed recovery.
- Strengthening exercises, focusing on your back, stomach, and leg muscles.
- Stretching exercises, which keep your muscles and other supporting tissues flexible and less prone to injury.
Some exercises can aggravate back pain. If you have low back pain, avoid:
- Straight leg sit-ups.
- Bent leg sit-ups or partial sit-ups (curl-ups) when you have acute back pain.
- Lifting both legs while lying on your back (leg lifts).
- Lifting heavy weights above the waist (standing military press or bicep curls).
- Toe touches while standing.
Lumbosacral region of the spine (lower back)
The spine is composed of 33 interlocking bones called vertebrae. The lumbosacral region of the spine consists of 5 lumbar vertebrae and the sacrum (5 bones joined together).
Sleeping positions for people with low back pain
From healthwise
General guidelines for sleeping:
- Sleep so that your back is in a neutral position. The neutral position keeps the back in its natural three front-to-back curves that give the spine an "S" shape.
- Place a pillow under your knees when sleeping on your back. You may also want to try using a towel roll to support your lower back.
- Place a pillow between your knees when sleeping on your side.
To rise from bed:
- Roll onto your side and bend both knees.
- Drop your feet over the side of the bed as you push with both arms to sit up.
- Scoot to the edge of the bed and position your feet under your buttocks.
- Stand up, keeping your back in the neutral position.
How can I lift without hurting my back?
Follow these basic rules to protect your back while lifting:
- Keep a wide base of support. Your feet should be shoulder width apart, with one foot slightly ahead of the other (karate stance).
- Squat down, bending at the hips and knees only. If necessary, put one knee to the floor and your other knee in front of you, bent at a right angle (half kneeling).
- Maintain good posture. Look straight ahead, and keep your back straight, your chest out, and your shoulders back. This helps keep your upper back straight while maintaining a slight arch in your lower back.
- Slowly lift by straightening your hips and knees (not your back). Keep your back straight, and don't twist as you lift.
- Hold the load as close to your body as possible, at the level of your belly button.
- Use your feet to change direction, taking small steps.
- Lead with your hips as you change direction. Keep your shoulders in line with your hips as you move.
- Set down your load carefully, squatting with the knees and hips only.
Follow these tips to avoid compressing the spinal discs or straining your lower back when lifting:
- Keep a wide base of support. Your feet should be shoulder-width apart, with one foot slightly ahead of the other (karate stance).
- Squat down, bending at the hips and knees only. If necessary, put one knee to the floor and your other knee in front of you, bent at a right angle (half kneeling).
- Maintain good posture. Look straight ahead, and keep your back straight, your chest out, and your shoulders back. This helps keep your upper back straight while maintaining a slight arch in your lower back.
- Slowly lift by straightening your hips and knees (not your back). Keep your back straight, and don't twist as you lift.
- Hold the load as close to your body as possible, at the level of your belly button.
- Use your feet to change direction, taking small steps.
- Lead with your hips as you change direction. Keep your shoulders in line with your hips as you move.
- Set down your load carefully, squatting with the knees and hips only.
Keep in mind:
- Do not attempt to lift by bending forward. Bend your hips and knees to squat down to your load, keep it close to your body, and straighten your legs to lift.
- Never lift a heavy object above shoulder level.
- Avoid turning or twisting your body while lifting or holding a heavy object.
Why is it important to be careful about lifting?
Back injury is best avoided at all costs. Once you have injured your back, it becomes more vulnerable to future injury. A back injury can alter your entire quality of life and possibly your livelihood, especially if it returns or becomes chronic.
Poor lifting technique can injure your back in various ways:
- Muscle or ligament strain—or tiny tears in the muscle or ligament—commonly results from a combination of poor body mechanics and too much of a burden on your back muscles.
- Spinal disc injury is often caused by forward bending of the spine and poor lifting technique. A spinal disc that is squeezed by the vertebrae above and below it can bulge or break open (herniated disc), causing back and leg pain and numbness (sciatica) and occasionally bowel and bladder problems.
- Vertebrae can become damaged during awkward lifting.
What types of lifting can cause injury?
Before focusing on the right way to lift, review the following common lifting mistakes that easily lead to a back injury:
- Allowing the back to curve forward while you grasp an object, then lifting by straightening the back
- Bending at the hips but keeping the legs straight while grasping and lifting
- Twisting the back while lifting or holding, usually by turning the shoulders, but not the hips
- Holding an object away from the body
- Lifting a heavy object (or child) above shoulder level
- Attempting to lift an object that's too heavy or awkward for one person to safely lift
- Underestimating the need to be careful when lifting a light object
Low back pain: Easing back into your daily activities
Bed rest of more than a couple of days can actually make your low back pain worse and lead to other problems such as stiff joints and muscle weakness.1 If you do use bed rest for a short time, remember the following guidelines.
- Sitting up in bed puts additional pressure on the intervertebral discs. Lying on your side puts a little more pressure on the discs than lying on your back.
- Trying to eat a meal in bed can be awkward and can put more strain on your back than if you just get up and eat at a table.
Avoid activities that make your pain worse. Modify activities that you cannot avoid doing. Here are some tips:
- Place one foot on a stool when standing for an activity such as brushing your teeth.
- When putting on pants or stockings, stand with your back against a wall. Then slide your shoulders down the wall as you bend your knees. Gently step into your pants or stockings, one leg at a time.
Return to your normal activity gradually, but as soon as possible. Start with walking 10 to 20 minutes every 2 to 3 hours.
First aid for low back pain
Illustration copyright 2003, 2005 Nucleus Communications, Inc. All rights reserved. http://www.nucleusinc.com
When you first feel back pain, try these steps to avoid or reduce pain:
- Apply ice. As soon as possible, apply ice or a cold pack to your injured back. You can apply ice for 15 to 20 minutes, 3 to 4 times a day, or as often as once every hour. Cold applied for the first 3 days limits swelling and reduces pain. You can use an ice pack or a bag of frozen vegetables wrapped in a thin towel.
- Relax. Find a comfortable position to rest. Some people are comfortable on the floor or a medium-firm bed with a small pillow under their head and another under their knees. Some people prefer to lie on their side with a pillow between their knees. Don't stay in one position for too long.
- Walk. Take a short walk (10 to 20 minutes) on a level surface (no slopes, hills, or stairs) every 2 or 3 hours. Walk only distances you can manage without pain, especially leg pain.
Build A Better Back Now
Keep your spine strong with six moves that provide stability and support.
Poor posture and back pain are common. Up to 80 percent of the population has experienced some back pain, according to several surveys. What’s worse is that intermittent back problems can worsen over time and become chronic.
While there are many kinds of back problems, and all with different causes, often, an underlying injury is associated with weaknesses in the surrounding muscles. Weak back muscles make you more vulnerable to stress, strains and pain in your spinal ligaments and discs. Plus, when certain back muscles are weak, others may over-compensate, leading to postural or muscular imbalances that further aggravate the load on your spine.
A strong, stable back is a healthier back, so including back-friendly moves into your regular workouts is crucial.
Following workouts is designed to mobilize, stabilize and strengthen the core muscles that surround your spine.
Build A Better Back Now
Build A Better Back Now
You’ll warm up with an easy back movement, undulating your spine to help loosen it and lubricate the joints. Exercises to strengthen your latissimus dorsi and rhomboids, along with other muscles, will help you stand up straight and erase slumping shoulders. Moves that use your abs and erector spinae in a variety of side-lying, face-down and face-up back-lying poses will help you develop spinal stability, especially in your lower back. The above mentioned moves concentrate on stabilizing your spine while it is straight, rather than bent. (Many people with weak backs find that “crunching” and “pelvic tilts” that flex, or bend, the back, can put too much stress on the spine.) Here, six moves to keep your spine strong.
HOW TO DO IT:
• Start by performing one set of each exercise, and work up to doing three sets.
• Warm up with five reps of the Spine Wave. Do eight to 12 reps of the two-band exercise as well as the Dead Bug. Do three to five reps of five- to 30-second static “holds” when performing the Side Plank and the Superman.
• Do this workout three times a week with a rest day in between.
• Modify this workout to match your fitness level. Follow the recommended moves, or adapt them as needed.
• If you experience any back pain, or have a history of back problems, always consult with a health professional who specializes in diagnosing and treating the spine.
• What you need: a towel and a resistance band.
From MSN Health
Timeline of a Tummy
From pregnancy to weight loss, tummies have their ups and downs. Exercise your way to a flatter core!
We do not enter this world with a flat belly, nor do we usually leave with one. And in between, even the sexiest stomach will have its ups and downs thanks to pregnancy, hormonal shifts, and Coffee Heath Bar Crunch. Wherever you are on the timeline, you can exercise your way to a firmer, flatter core.
Teens and 20s
Estrogen is acting like a busy traffic cop, directing fat storage to the breasts, hips, and thighs. The belly, however, is spared. So now's the time to work it. "Belly dancing celebrates the flesh," says Anita-Cristina Calcaterra, one of a joyously gyrating Boston trio known as the Goddess Dancing, who suggests this great move for a strong and sensuous stomach.
Begin by standing facing a full-length mirror with legs hip-width apart, knees bent softly, tailbone tucked, and chest lifted.
Heart circles: Imagine using your breasts to draw a vertical O in the mirror. First, lift up from your diaphragm. Keeping your hips still, in a continuous motion, slide your chest directly to the left, then down toward your belly button, across to the right side, and back up to where you started. Do for five minutes a day in both directions.
After Pregnancy
Few bellies obligingly snap back into shape without serious prodding. Discuss exercise with your doctor or midwife: In most cases, you can take gradually longer walks and move on to more vigorous activity after six weeks.
Elizabeth Trindade, founder of Strollercize, suggests these waist whittlers to get you started. Do five reps at a time, slowly working up to 50 reps throughout the day for both exercises combined.
Couch crunch: Sit at the edge of a sofa with your feet out and on the floor and hands on your stomach. Relax your thighs and turn them slightly outward, then roll back until your bra line just touches the sofa back. Pull in your abdomen and lift one or both feet off the floor. In that position, contract your abs even more as you exhale to a count of 10. Return feet to the floor, sit tall, and relax.
Roll away: Stand sideways behind the stroller (occupied, of course) and grasp the handle with your closer hand. Push the stroller away while slightly bending your knees and sticking out your bottom a bit. Pull the stroller back toward you while straightening up. After five reps, repeat with the other arm (both sides equal 10 reps).
Menopause
As estrogen downshifts, fat is rerouted toward the upper body and waist. Dubbed the menopot by Pamela Peeke, MD, author of Body for Life for Women, the middle-aged pouch differs from the excess visceral abdominal fat that's linked to heart problems, diabetes, and cancer. The only downside of the menopot, she says, is "a little consternation when you're trying to zip up your skirt or pants in the morning." Focused efforts—including regular cardio that pares calories —help flatten it.
Yoga: Under pressure, women often eat more—especially sugary treats, which help quell the stress hormone cortisol. So take up yoga, meditate regularly, or at least learn to breathe deeply (not graze avidly) when the stress ratchets up.
Core work: Lie on your back with your knees bent and feet flat on the floor. Raise the lower legs until parallel to the floor, knees still bent and arms relaxed at your sides, palms down. Without using your hands to press, pull in your abs and lift your hips (it feels like a rocking motion) a few inches off the ground. Do three sets: first, 12 to 20 reps; second, 12 to 15 reps; third, eight to ten reps. Rest a minute between sets.
It won't take a day. It won't take a week. But with a little (okay, a lot of) tender loving exercise—some might call it tough love—your tummy can defy the rise and fall of nature's timeline and stay winningly tight.
From MSN Health
Monday, April 28, 2008
More Liver
One of the liver's most important overall functions is maintaining nutrient homeostasis. It controls the blood level of a number of macro- and micronutrients, and attempts to keep them all at optimal levels.
Here's a list of some of the liver's functions I'm aware of:
- Buffers blood glucose by taking it up or releasing it when needed
- A major storage site for glycogen (a glucose polymer)
- Clears insulin from the blood
- Synthesizes triglycerides
- Secretes and absorbs lipoprotein particles ("cholesterol")
- Stores important vitamins: B12, folate, A, D, E, K (that's why it's so nutritious to eat!)
- Stores minerals: copper and iron
- Detoxifies the blood
- Produces ketone bodies when glucose is running low
- Secretes blood proteins
- Secretes bile
- Converts thyroid hormones
- Converts vitamin D (D3 --> 25(OH)D3)
More Liver
One of the liver's most important overall functions is maintaining nutrient homeostasis. It controls the blood level of a number of macro- and micronutrients, and attempts to keep them all at optimal levels.
Here's a list of some of the liver's functions I'm aware of:
- Buffers blood glucose by taking it up or releasing it when needed
- A major storage site for glycogen (a glucose polymer)
- Clears insulin from the blood
- Synthesizes triglycerides
- Secretes and absorbs lipoprotein particles ("cholesterol")
- Stores important vitamins: B12, folate, A, D, E, K (that's why it's so nutritious to eat!)
- Stores minerals: copper and iron
- Detoxifies the blood
- Produces ketone bodies when glucose is running low
- Secretes blood proteins
- Secretes bile
- Converts thyroid hormones
- Converts vitamin D (D3 --> 25(OH)D3)
More Liver
One of the liver's most important overall functions is maintaining nutrient homeostasis. It controls the blood level of a number of macro- and micronutrients, and attempts to keep them all at optimal levels.
Here's a list of some of the liver's functions I'm aware of:
- Buffers blood glucose by taking it up or releasing it when needed
- A major storage site for glycogen (a glucose polymer)
- Clears insulin from the blood
- Synthesizes triglycerides
- Secretes and absorbs lipoprotein particles ("cholesterol")
- Stores important vitamins: B12, folate, A, D, E, K (that's why it's so nutritious to eat!)
- Stores minerals: copper and iron
- Detoxifies the blood
- Produces ketone bodies when glucose is running low
- Secretes blood proteins
- Secretes bile
- Converts thyroid hormones
- Converts vitamin D (D3 --> 25(OH)D3)
More Liver
One of the liver's most important overall functions is maintaining nutrient homeostasis. It controls the blood level of a number of macro- and micronutrients, and attempts to keep them all at optimal levels.
Here's a list of some of the liver's functions I'm aware of:
- Buffers blood glucose by taking it up or releasing it when needed
- A major storage site for glycogen (a glucose polymer)
- Clears insulin from the blood
- Synthesizes triglycerides
- Secretes and absorbs lipoprotein particles ("cholesterol")
- Stores important vitamins: B12, folate, A, D, E, K (that's why it's so nutritious to eat!)
- Stores minerals: copper and iron
- Detoxifies the blood
- Produces ketone bodies when glucose is running low
- Secretes blood proteins
- Secretes bile
- Converts thyroid hormones
- Converts vitamin D (D3 --> 25(OH)D3)
The Liver: Your Metabolic Gatekeeper
I read a paper today from the lab of C. Ronald Kahn that really drove home the point. They created a liver-specific insulin receptor knockout (LIRKO) mouse, which is a model of severe insulin resistance in the liver. The mouse ends up developing severe whole-body insulin resistance, dramatically elevated post-meal insulin levels (20-fold!), impaired glucose tolerance, and elevated post-meal and fasting glucose. Keep in mind that this all resulted from nothing more than an insulin resistant liver.
LIRKO mice had elevated post-meal blood glucose due to the liver's unresponsiveness to insulin's command to take up sugar. Apparently the liver can dispose of one third of the glucose from a meal, turning it into glycogen and triglycerides. The elevated fasting glucose was caused by insulin not suppressing gluconeogenesis (glucose synthesis) by the liver. In other words, the liver has no way to know that there's already enough glucose in the blood so it keeps on pumping it out. This is highly relevant to diabetics because fasting hyperglycemia comes mostly from increased glucose output by the liver. This can be due to liver insulin resistance or insufficient insulin production by the pancreas.
One of the interesting things about LIRKO mice is their dramatically elevated insulin level. Their pancreases are enlarged and swollen with insulin. It's as if the pancreas is screaming at the body to pick up the slack and take up the post-meal glucose the liver isn't disposing of. The elevated insulin isn't just due to increased output by the pancreas, however. It's also due to decreased disposal by the liver. According to the paper, the liver is responsible for 75% of insulin clearance from the blood in mice. The hyperinsulinemia they observed was both due to increased secretion and decreased clearance. Interestingly, they noted no decline in beta cell (the cells that secrete insulin) function even under such a high load.
Something that's interesting to note about these mice is they have very low blood triglyceride. It makes sense since insulin is what tells the liver to produce it. Could this have something to do with their lack of beta cell dysfunction?
The really strange thing about LIRKO mice is that their blood glucose becomes more normal with age. Strange until you see the reason: their livers are degenerating so they can't keep up glucose production!
LIRKO mice reproduce many of the characteristics of type II diabetes, without degenerating completely into beta cell death. So insulin resistance in the liver appears to reproduce some elements of diabetes and the metabolic syndrome, but the full-blown disorders require other tissues as well. As a side note, this group also has a skeletal muscle-specific insulin receptor knockout which is basically normal. Interesting considering muscle tissue seems to be one of the first tissues to become insulin resistant during diabetes onset.
So if you want to end up like your good pal LIRKO, remember to drink high-fructose corn syrup with every meal! You'll have fatty liver and insulin resistance in no time!
I have a lot more to say about the liver, but I'll continue it in another post.
The Liver: Your Metabolic Gatekeeper
I read a paper today from the lab of C. Ronald Kahn that really drove home the point. They created a liver-specific insulin receptor knockout (LIRKO) mouse, which is a model of severe insulin resistance in the liver. The mouse ends up developing severe whole-body insulin resistance, dramatically elevated post-meal insulin levels (20-fold!), impaired glucose tolerance, and elevated post-meal and fasting glucose. Keep in mind that this all resulted from nothing more than an insulin resistant liver.
LIRKO mice had elevated post-meal blood glucose due to the liver's unresponsiveness to insulin's command to take up sugar. Apparently the liver can dispose of one third of the glucose from a meal, turning it into glycogen and triglycerides. The elevated fasting glucose was caused by insulin not suppressing gluconeogenesis (glucose synthesis) by the liver. In other words, the liver has no way to know that there's already enough glucose in the blood so it keeps on pumping it out. This is highly relevant to diabetics because fasting hyperglycemia comes mostly from increased glucose output by the liver. This can be due to liver insulin resistance or insufficient insulin production by the pancreas.
One of the interesting things about LIRKO mice is their dramatically elevated insulin level. Their pancreases are enlarged and swollen with insulin. It's as if the pancreas is screaming at the body to pick up the slack and take up the post-meal glucose the liver isn't disposing of. The elevated insulin isn't just due to increased output by the pancreas, however. It's also due to decreased disposal by the liver. According to the paper, the liver is responsible for 75% of insulin clearance from the blood in mice. The hyperinsulinemia they observed was both due to increased secretion and decreased clearance. Interestingly, they noted no decline in beta cell (the cells that secrete insulin) function even under such a high load.
Something that's interesting to note about these mice is they have very low blood triglyceride. It makes sense since insulin is what tells the liver to produce it. Could this have something to do with their lack of beta cell dysfunction?
The really strange thing about LIRKO mice is that their blood glucose becomes more normal with age. Strange until you see the reason: their livers are degenerating so they can't keep up glucose production!
LIRKO mice reproduce many of the characteristics of type II diabetes, without degenerating completely into beta cell death. So insulin resistance in the liver appears to reproduce some elements of diabetes and the metabolic syndrome, but the full-blown disorders require other tissues as well. As a side note, this group also has a skeletal muscle-specific insulin receptor knockout which is basically normal. Interesting considering muscle tissue seems to be one of the first tissues to become insulin resistant during diabetes onset.
So if you want to end up like your good pal LIRKO, remember to drink high-fructose corn syrup with every meal! You'll have fatty liver and insulin resistance in no time!
I have a lot more to say about the liver, but I'll continue it in another post.
The Liver: Your Metabolic Gatekeeper
I read a paper today from the lab of C. Ronald Kahn that really drove home the point. They created a liver-specific insulin receptor knockout (LIRKO) mouse, which is a model of severe insulin resistance in the liver. The mouse ends up developing severe whole-body insulin resistance, dramatically elevated post-meal insulin levels (20-fold!), impaired glucose tolerance, and elevated post-meal and fasting glucose. Keep in mind that this all resulted from nothing more than an insulin resistant liver.
LIRKO mice had elevated post-meal blood glucose due to the liver's unresponsiveness to insulin's command to take up sugar. Apparently the liver can dispose of one third of the glucose from a meal, turning it into glycogen and triglycerides. The elevated fasting glucose was caused by insulin not suppressing gluconeogenesis (glucose synthesis) by the liver. In other words, the liver has no way to know that there's already enough glucose in the blood so it keeps on pumping it out. This is highly relevant to diabetics because fasting hyperglycemia comes mostly from increased glucose output by the liver. This can be due to liver insulin resistance or insufficient insulin production by the pancreas.
One of the interesting things about LIRKO mice is their dramatically elevated insulin level. Their pancreases are enlarged and swollen with insulin. It's as if the pancreas is screaming at the body to pick up the slack and take up the post-meal glucose the liver isn't disposing of. The elevated insulin isn't just due to increased output by the pancreas, however. It's also due to decreased disposal by the liver. According to the paper, the liver is responsible for 75% of insulin clearance from the blood in mice. The hyperinsulinemia they observed was both due to increased secretion and decreased clearance. Interestingly, they noted no decline in beta cell (the cells that secrete insulin) function even under such a high load.
Something that's interesting to note about these mice is they have very low blood triglyceride. It makes sense since insulin is what tells the liver to produce it. Could this have something to do with their lack of beta cell dysfunction?
The really strange thing about LIRKO mice is that their blood glucose becomes more normal with age. Strange until you see the reason: their livers are degenerating so they can't keep up glucose production!
LIRKO mice reproduce many of the characteristics of type II diabetes, without degenerating completely into beta cell death. So insulin resistance in the liver appears to reproduce some elements of diabetes and the metabolic syndrome, but the full-blown disorders require other tissues as well. As a side note, this group also has a skeletal muscle-specific insulin receptor knockout which is basically normal. Interesting considering muscle tissue seems to be one of the first tissues to become insulin resistant during diabetes onset.
So if you want to end up like your good pal LIRKO, remember to drink high-fructose corn syrup with every meal! You'll have fatty liver and insulin resistance in no time!
I have a lot more to say about the liver, but I'll continue it in another post.
The Liver: Your Metabolic Gatekeeper
I read a paper today from the lab of C. Ronald Kahn that really drove home the point. They created a liver-specific insulin receptor knockout (LIRKO) mouse, which is a model of severe insulin resistance in the liver. The mouse ends up developing severe whole-body insulin resistance, dramatically elevated post-meal insulin levels (20-fold!), impaired glucose tolerance, and elevated post-meal and fasting glucose. Keep in mind that this all resulted from nothing more than an insulin resistant liver.
LIRKO mice had elevated post-meal blood glucose due to the liver's unresponsiveness to insulin's command to take up sugar. Apparently the liver can dispose of one third of the glucose from a meal, turning it into glycogen and triglycerides. The elevated fasting glucose was caused by insulin not suppressing gluconeogenesis (glucose synthesis) by the liver. In other words, the liver has no way to know that there's already enough glucose in the blood so it keeps on pumping it out. This is highly relevant to diabetics because fasting hyperglycemia comes mostly from increased glucose output by the liver. This can be due to liver insulin resistance or insufficient insulin production by the pancreas.
One of the interesting things about LIRKO mice is their dramatically elevated insulin level. Their pancreases are enlarged and swollen with insulin. It's as if the pancreas is screaming at the body to pick up the slack and take up the post-meal glucose the liver isn't disposing of. The elevated insulin isn't just due to increased output by the pancreas, however. It's also due to decreased disposal by the liver. According to the paper, the liver is responsible for 75% of insulin clearance from the blood in mice. The hyperinsulinemia they observed was both due to increased secretion and decreased clearance. Interestingly, they noted no decline in beta cell (the cells that secrete insulin) function even under such a high load.
Something that's interesting to note about these mice is they have very low blood triglyceride. It makes sense since insulin is what tells the liver to produce it. Could this have something to do with their lack of beta cell dysfunction?
The really strange thing about LIRKO mice is that their blood glucose becomes more normal with age. Strange until you see the reason: their livers are degenerating so they can't keep up glucose production!
LIRKO mice reproduce many of the characteristics of type II diabetes, without degenerating completely into beta cell death. So insulin resistance in the liver appears to reproduce some elements of diabetes and the metabolic syndrome, but the full-blown disorders require other tissues as well. As a side note, this group also has a skeletal muscle-specific insulin receptor knockout which is basically normal. Interesting considering muscle tissue seems to be one of the first tissues to become insulin resistant during diabetes onset.
So if you want to end up like your good pal LIRKO, remember to drink high-fructose corn syrup with every meal! You'll have fatty liver and insulin resistance in no time!
I have a lot more to say about the liver, but I'll continue it in another post.
Let's Heal From the Inside Out
I've been working with a great trainer and friend of mine, Ben. We've been going hard for about a month. You see, people, just like I preach to you, I switch it up. I'm doing tons of things I'm not good at or don't like, but that are really helping me. I'm even seeing subtle changes that I like in my physique.
My point? Well, Ben handed me a couple of notebooks and a few pens the other day and said "Journal." We'd talked about my injury, and I felt like I was holding onto it for some reason. It's easy to just cast something aside and say, "It's not getting better," but why isn't it getting better? So I started journaling trying to get whatever is inside out on paper. Outside of me. Away from me.
To be honest, I've come to a place where I realize if I don't deal with my knee now, it will hurt for the rest of my life. I'm not saying real injuries don't happen, but often times a "permanent" injury is a reflection of something else. Yes, my knees hurt because of over-use and bad mechanics. However, there's something within me that's using the injury to hold me back. Maybe it's safe. Or an excuse. Do you have anything like that in your life? Maybe it's a sickness or some extra pounds that you're keeping on to protect you or isolate you from life. I know I'm doing it, and I'm tired of it. I'm going to write until I unload the self-sabotaging crap that's inside me. You can still be performing and holding back just a little bit. I work hard, I'm disciplined and focused, and even within that framework, I believe I'm trying to just hold back a bit.
It's scary to go for it all the way. But I figure if we're here among the living, why don't we just put it all out there? If I fail, I fail. That's part of living, and I think once we do it a few times, we realize we survive and end up learning something. Maybe you're using it to hide from love? Love hurts, but the price is so worth it.
Get your pen and paper. Write it all down. Fear, pain, sadness, joy, dreams, the past -- whatever it is, get it out.
So I want to tell you to exercise more often and eat healthy for the obvious reasons. If you're not there yet, then ask yourself what's holding you back? Don't give me the "I don't know what to eat" or "I don't have time" or "I get bored." Let's have the truth. It's time for all of us to be as free as we can. Let's heal from the inside out.
From Yahoo health
Don't Look Where You Don't Want to Go
I was talking with my college volleyball coach, Cecile, and she was saying she wants to write a book on positive coaching. So instead of saying "don't drop your arms, or straighten your legs," you instead tell the individual what you want them to do. You reinforce the positive thoughts and behaviors, and don't even bring up the stuff you don't want them to do.
Here we are going into a new year, and everyone is scrambling to make a fresh start. I have a proposal. What if your list or resolution only had the actions you wanted to do? Don't write down things like "I'm not going to eat dinner after 6 p.m." Write down that your aim is to eat before 7 p.m. It's not about "I'm not going to eat sweets and drink alcohol." Try "I'm going to eat more fruit I enjoy and reach for water whenever I am thirsty." Look in the direction you want to travel, not at the cliff you are trying to avoid falling off.
If you know you're going to reach for food when the stress hits, resolve that you will walk around the block when you are having a stressful situation. Another really simple and helpful technique is taking 2 minutes (literally) to breathe. When you are ready to scream at the kids or the knucklehead driver in front of you, take 5 deep, deep breaths. Get your body to calm down for a second before you react. You'll be amazed at how effective this simple technique is.
If you're trying to make some changes in your life, then focus on the good. Notice the progress. Stop looking at what isn't the way you want it yet. If you keep looking at your positive attributes and take baby steps, you will keep looking ahead. By focusing on "I'm too heavy" or "I ate poorly at lunch today," you'll continue to reinforce that pattern in your body, your life, and your thoughts and beliefs.
Keep your eyes on the road and believe. If, once in a while, you're looking at that guardrail out of the corner of your eye, that's OK. It's good to be in touch with our weaknesses, but keep that car on the pavement.
Here's to the journey and all the destinations we reach along the way. Happy New Year.
From yahoo health
My Be Healthy Top 10 List
- Exercise. I find this to be the one medicine that works well with all ailments. Even when I'm tired, exercise is my cure-all. Crazy husband or kids, stress at work, my time of the month psychoticness, questioning my existence and wondering "what does it all mean?" -- exercise gives me some grounding, a release and clarity.
- Lean, real food. Real food (not from a drive-thru window or a microwave) can influence my mood. I feel so much more energized and level when I eat living food. What does that mean? Something that hasn't been deep fried to a yummy tasting death, zapped or frozen to the point of non existent nutrients. Is it tricky? Does it take more effort? Yup! Are there times I would rather have a meal that tastes so good, arrives so quick, and hurts after the fact? Yup! But we're living beings with organs working hard on our behalf. Food with nutrients and enzymes helps all of that flow so much smoother. My blood sugar levels (influences things like one's energy levels, mood and ability to concentrate) stabilize. Eat something green with every meal and don't be afraid of food and calories. Yes, watch the portions, but not to the extent where you starve yourself. We all have to eat to be healthy.
- Sleep. We can't recover if we don't get some rest. I'm not going to tell you how much sleep to get, but you know for yourself how much you need to feel rested. I suggest getting to bed as early as you possibly can. Remember, they use sleep deprivation as a form of torture during wartime, and there's a good reason why. New moms and dads, it's going to pass.
- Feelings of happiness. I'm not the type of person that walks around "la la la." I'm just saying within your personality type, can you find the smile? The joy? Search for the happiness in your own way, and express it in your own way. Find the peace. Believe me, the top 3 make this easier.
- Have a passion. It helps me to be healthy if I have things in my life that I like to do and that challenge me. Gets me fired up to get out of bed on the days I feel hum drum. Find a passion that is just for you and is yours. It can be something that benefits others, but it's your passion.
- Love. Friends and/or family. Someone to love and who loves you. We all need nurturing in this world. I'm not talking about romantic love. I'm talking about another spirit to connect with and offer support.
- Fun. I have to remind myself that we're not here on this planet to just grind away. Laugh. Enjoy. Hang out. Be silly. Just have some fun...
- Water. I gave water its own number, because I think it's that important. Oh, by the way, I read a great stat. We get 21% of our calories from what we drink. Last time I checked, water didn't have any calories. So by just drinking water, you could cut down on 1/5 of your caloric intake and do your body, skin, and butt a huge favor. Beware of the sugar drinks -- even the "healthy ones."
- Spirit. We're all in this together. I find that if I'm nice to my fellow human or do something for someone else, it's good for me. See? Even within your unselfishness, you can be selfish.
- I know it's gross, but we can't forget going to the bathroom. We need to go regularly. If stuff is going in, then it has to come out. The water and good food help with this.
- Balance (this is the bonus checklist item -- extra credit if you will). That's right, the "b" word. I'm just trying to keep it all balanced, because it feels the best when I even get close to working the balance act out.
From Yahoo health
Don't Underestimate the Those Rose-Colored Glasses
But there are those people who leave comments that are totally off the wall. Maybe they're upset that my picture doesn't show me smiling. Or maybe they question how I would know about some of these real-world problems since I live a "celebrity life." Fair enough. I call that Internet bravery, and it teaches me an important lesson -- we see everything in life tinted by the glasses we wear. So if people are that upset with me (and they don't even know me) when all I'm trying to do is be a cheerleader, I wonder how frustrated they are with the rest of their lives.
My husband always told me that if he was looking for a fight he could jump in his car and chances are the first driver he came across would be willing to give him a rub. The point is I'm grateful for all of the remarks, because they continue to remind me that I believe in trying to be healthy. I'm not perfect. I'm not a saint. I take pictures without a smile from time to time. I overreact. I don't even have a few of the answers, but I'm committed to carrying the message of the importance of my health and your health.
Within a very simple formula are a lot of complex issues. Losing weight and being healthy are all about what food you put in your mouth and how often you move. This is basic stuff, so maybe it should be handled with a basic approach. Does stress or unhappiness affect your waistline? Of course -- 100%. That is the X factor. I'm certainly not qualified to even get into identifying this component. However, I've realized that a lot of the remarks on my blog are from individuals whose glasses are tinted with just enough unhappiness that they're seeking out conflict. Which brings me to the most critical issue of all - responsibility.
Believe it or not, my life is not perfect. However, I've always tried (and sometimes failed) to only point the finger at myself. At least if we own our reality, we can make the change. If we're blaming some other person or situation, then we've lost the control to make the change that we "say" we want. So in this blog entry, there will be no lists. Just a few simple questions...
- Can you eat healthier?
- What's stopping you?
- Are you able to do some form of exercise?
- What's keeping you from doing it?
- If you aren't happy, why not?
- Is there something you can do to make yourself feel better?
- If someone has screwed you in some way (a lover or a parent), can you find the way to break away from that influence? Can you forgive? Move on?
- If you have loads of stress, is there one thing you can do to alleviate it? One thing?
If you want to send me angry comments, no problem, but in the interim see if there's some way you can wipe off your glasses and see things through rosy-colored lenses. There is good in us and our lives -- we just have to be able to see it. I promise next week will be a big fat list.
Peace, happiness, and good health,
Gabby
From Yahoo health
Figuring out What Matters
What a laugh. Control. It's really started to bother me. I've been feeling like a dog chasing it's tail, and I'm sure it's fun to watch. Since I don't like to admit to or react to stress, I just carry a little extra pressure that seems to go to my eyeballs.
Last week I had a "let go" moment. I saw myself overreact to a no-big-deal situation, and I realized that I was letting it get to me. I also noticed that because I was extra busy and wasn't getting the time I needed to work out, I began to slip ever so subtly. I was on the road and out of my routine. If I don't consistently get the time I need to work out, I feel it defeating me in all the other areas of my life (food, sleep, I was a tad more grumpy, and even watched more TV).
I see how easily it becomes a downward spiral. How you could feel like you can never get a leg up one day, and then it turns into weeks, months, and years. Not to mention when we don't get our time, we eat crap to soothe ourselves, waste more time watching TV about other people's train wrecks of lives to make us feel better, and are just less pleasant to our loved ones. Cause when I have pressure in my eyeballs, I'm just not as nice.
So I took a step back and asked myself how I could better deal with things. I'm not going to sacrifice my health (physical, mental, or emotional) for anything. So there is a commitment. Now I'm going to take the emotion out of it since I used that to make the commitment. I have decided. This is a priority.
OK, what about the stress? My husband said that it was human to react. I thought it was foolish since the situation was not life or death. Let's face it, sometimes it just feels good to let it out. Yell a little (if it's not hurting anyone) or even go in the bathroom and have a good cry. Wash your face and charge.
Who said I was behind? I did. I've been creating the stress. As long as you don't forget your kids at school, how much of what you run around to get done is really that vital? If everyone is fed and clean, isn't it OK if I don't worry about every house detail until the morning?
I realized that if I didn't get up first thing and go exercise, it was going to get harder and harder to get things accomplished as the day went on. Some mornings I just get up, put my gym clothes on, and GO! Take a shower, brush your teeth, and call people back after you exercise. Even if you just get in 30 minutes, that's the way to start the day. Take a walk and meditate at the same time. I've even heard of people who talk to God on their morning hustles. It starts you off in the right direction so you can face the rest of the day.
Of course we have stressful lives. We live in a fast-paced world that can be crazy. I stand by the idea that exercise and eating well actually armor you to defend yourself during the hectic navigation.
I am going to keep a short list of things that are important, and I'm going to make sure those get done. I have to let go of every detail and not list everything with equal importance. Sometimes just stopping and realizing what's going on is the most important step. I just want to keep trying to be the dog that wags the tail and not the other way around.
Life isn't perfect and neither am I, so why do I keep trying to make it all just so? Why not just enjoying myself and the people I love? Have I been doing that? I gotta believe that there is no finish line, so maybe I should pace myself and enjoy this process of living.
I made my list:
- Be thankful for everything, even the hard stuff.
- Take care of my health (eat well and exercise).
- Be the best mom and wife I can for my family.
- Try to be kind, and add something to this place I'm living on.
- Work hard and stand up for what I believe.
So that's my short list. If things fall under one of those umbrellas, then I'm dead serious. Everything else, I'm going to try and keep perspective on it. Hey and if I blow it, the great news is I can keep trying.
From Yahoo health
Do Something Radical for 14 Days
I have a wonderful friend named Don who told me we are crazy when we do the same thing over and over expecting a different result. As if somehow this time will be different...come on! No handholding. Let's do it.
I train hard, eat healthy, and am in good shape, but I am tighter than all get-out, and it's starting to affect my body. For example, I believe I could have improved the health of my knee if my hips, feet, and IT bands were not so tight. I hate stretching and it hurts like a mother. I love chocolate. I have gotten into the habit of eating it all the time. I don't drink coffee or alcohol, but chocolate is my pacifier.
So for the past week (and I have another week to go) I have been fasting (eating only soft veggies, eggs, and smoothies with protein) and taking yoga. Why? I need to change and I wasn't able to pull it off just going along day after day in my life. So I am committing this time to redirect my ship. I feel hungry and my husband can tell you I have been just a little more direct (which is a nice way of saying edgy). My three-year-old asked me why I was so grumpy. You get the point.
When I'm in the thick of it, I just keep telling myself that it's only for 14 days and I will have moved closer to better habits. My body feels better and even my knees and other joints feel great. No processed sugar. Less inflammation in my body.
Now you pick an area or areas in your life and commit 14 days to do or die doing it better:
- Create the goal. Really see where the need is.
- There is no perfect time, but start in a window that is somewhat realistic to your life.
- If you can, do it with a friend. Support is key. If you have someone you can go through it with, that makes it so much easier.
- When you are in the thick of it, see what changes are occurring and focus on all the good that you are doing for yourself.
- Commit. Don't quit!!!!!
So if you need to get some exercise in your life, make a workout calendar. Write it all down and do not break that date. If you say you want to eat better, then suck it up for 14 days. This is not a diet, this is boot camp. This is you and me changing our day-to-day habits with a sledgehammer. It's just 14 days.
I'm of the belief that once you see that you can do it on an extreme level, you will be able to pick and choose so much easier in your day-to-day life. You will be able to implement better habits. Do something drastic, and let's rewrite the ending to our same old stories. Why not? What do you have to lose?
Don't Let Stress Get You
Don't let the stress get you. Do it for the dog.
Do you ever feel like you're living right on the emotional edge? For the most part, I think I'm a fairly calm person. But since my younger daughter turned 3, I feel like I've been just short of "snap" for the past 4 months. Patience? Bite me. I've been walking around with a tightness in my chest, and I'm ready to kick the dog. The monotony of life can get a hold of you and control you. I exercise regularly and eat really healthy. But sometimes that doesn't feel like enough to help cope with that edginess. I even catch myself looking to place blame on my husband or something else external in my life.
Is this human? I believe so. However, I don't think it's the way it's designed or has to be. Isn't it really about looking within if we're feeling unhappy or stressed? Now, I'm not saying there we don't have to deal with stressful stuff, but how we react to it or allow it to affect us is our responsibility. Are there little things we can do to try and improve the affects of stress, monotony, and the human condition? Absolutely.
- Own the feeling and blame no one. If you feel a certain way, express it. Don't indulge but recognize how you're feeling. Next, do not blame anyone or thing. Own the entire situation.
- Get involved. If you don't like the way things are, get involved and be a part of the change and solution.
- Move. No, not your address, your butt. Just get out several times a week and sweat and feel your heart pump. That heart beating will remind you that you're alive. Realizing that you are with the living on a regular basis is a gift. Appreciating life and not just "living it one day to the next" help your perspective.
- Change the way you see it. Sometimes it can be almost as easy as shifting your point of view about a circumstance. A screaming baby is healthy enough to cry. Sitting in traffic means not being in an accident. Can you find the good and not dwell on the bad or difficult?
- Eat healthy. Food affects your brain, body, and mood. Try to find a way to not go up and down with sugar, caffeine, and alcohol. People, listen to me -- food does impact us.
- Make time for fun. Dance, laugh, hang with friends, travel, go on an adventure, snuggle with family, take a bath, hike, go for a bike ride, read a great book, enjoy a beautiful meal. Just do stuff whenever you can that is fun. It's not always about work, school lunches, and folding the laundry. Yes, those things have to get done, but can you squeeze in some fun?
- Connect with your spiritual side. (I'm going out on a limb here -- people have strong opinions about this topic). God, Buddha, nature -- whatever god is for you. Why? This is the essence of life. Plus I often feel like if I'm accountable for my spiritual life, I will continue to keep trying. Trying to do the right thing. Trying to see the positive and the blessings. To have a guide.
- Laugh when you think it sucks. You know -- when you're having "one of those days," and it's one nutty thing or person after the next. Learn to laugh.
- Stretch and breathe. Most of us don't take 10 deep belly breaths a day. We walk around shallow chest breathing all day long. Deep breaths help your body process stress. When you're driving in your car, make an effort to take nice deep breaths. Next thing is stretch out your body. We sit in chairs and cars all day long, and we need to stretch out our muscles and joints. It can feel so good. Just do it 5-15 minutes a day on the floor in front of the TV.
- Make sure you're getting enough rest. Sleep deprivation is a form of torture for a reason. Lack of sleep will make you cuckoo.
- Don't be a victim.
- This is yours to fill out.
So here's to the wonderful and challenging journey called life. We will never be perfect, but we can always strive to do better. I don't want to be a crazy lady who my children roll their eyes at and my dogs run from.
From Yahoo health