Antioxidant vitamins intake and the risk of coronary heart disease: meta-analysis of cohort studies.
Ye Z and Song H.
Eur J Cardiovasc Prev Rehabil. 2008;15:26-34.
This meta-analysis of 15 cohort studies examined associations between antioxidant vitamins (vitamins C, E, and beta-carotene) and coronary heart disease (CHD) risk. Dietary intake of vitamins C and E and supplement use of vitamin E were associated with a lower CHD risk, whereas supplement use of vitamin C had no significant association with CHD risk.
Antioxidant therapy attenuates oxidative stress in chronic cardiopathy associated with Chagas' disease.
MaƧao LB et al.
Int J Cardiol. 2007;123:43-9.
In 40 chronic chagasic patients, vitamin E (800 IU/day) and vitamin C (500 mg/day) supplementation for 6 months counteracted the progressive oxidative stress associated with the disease. The researcherssuggest that future treatment of Chagas' disease might include an antioxidant therapy.
Antioxidant vitamins reduce oxidative stress and ventricular remodeling in patients with acute myocardial infarction.
Gasparetto C et al.
Int J Immunopathol Pharmacol. 2005;18:487-96.
Patients with myocardial infarction undergoing reperfusion therapy given antioxidant vitamins before and for 1 month after reperfusion experienced improvements in the antioxidant system and reductions in oxidative stress, the inflammatory process and left ventricular remodelling.
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