* This meta-analysis of 5 studies examined the possible protective effect of vitamin D against colorectal cancer.
* The odds for developing colorectal cancer dropped as serum vitamin D levels increased; people with serum vitamin D levels ?33 ng/ml had a 50% lower risk than those with levels ?12 ng/ml.
* Based on these results it was suggested that a daily intake of 1000–2000 IU vitamin D3 might protect against colorectal cancer.
Shaun’s comment: Meta-analysis can be a powerful statistical tool that can be used to clarify areas of uncertainty from groups of individual studies. Generally, studies have more power to detect true effects when they are larger, and the technique of meta-analysis involves adding the data from similar studies together in order to determine the true result. In this analysis, the results indicated that taking vitamin D does actually prevent the occurrence of colorectal cancer.
Study reference:
http://dx.doi.org/10.1016/j.amepre.2006.11.004
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