Thursday, October 22, 2009

Evidence for...Magnesium for high blood pressure

Dietary magnesium intake and risk of incident hypertension among middle-aged and older US women in a 10-year follow-up study
Song Y et al.
Am J Cardiol. 2006;98:1616-21.
During a 10-year follow-up period, 8544 participants in the US Women's Health Sutdy developed incident hypertension. After adjustment for age and treatment allocation, dietary magnesium intake was inversely associated with the risk for developing hypertension; women with the highest intakes (median 434 mg/day) had a lower risk of developing hypertension compared with those with the lowest intakes (median 256 mg/day).


Potassium magnesium supplementation for four weeks improves small distal artery compliance and reduces blood pressure in patients with essential hypertension.
Wu G et al.
Clin Exp Hypertens. 2006;28:489-97.
In patients with essential hypertension, magnesium potassium supplementation (magnesium, 70.8 mg/day; potassium, 217.2 mg/day) for four weeks decreased systolic and diastolic blood pressure and increased large arterial compliance and small arterial compliance.


Magnesium in hypertension, cardiovascular disease, metabolic syndrome, and other conditions: a review.
Champagne CM.
Nutr Clin Pract. 2008;23:142-51.
This review of current literature on the role played by magnesium in chronic, disease-related conditions notes that magnesium plays a major role in the regulation of blood pressure. Evidence indicates an inverse relationship between magnesium intake and blood pressure, which is strongest for magnesium obtained from food rather than that obtained via supplements. Hypertension associated with preeclampsia appears to be alleviated when magnesium is administered; in addition, women with adequate intakes of magnesium are less likely to be affected by preeclampsia than those with an inadequate intake.

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